Folate system correlations in DNA microarray data

cDNA Microarray Data Normalization

Normalizing DNA microarray data.

DNA microarrays are a powerful tool to investigate differential gene expression for thousands of genes simultaneously. Although DNA microarrays have been widely used to understand the critical events underlying growth, development, homeostasis, behavior and the onset of disease, the management of the resulting data has received little attention. Presently, the fluorescent dyes Cy3 and Cy5 are m...

Identification and correction of spurious spatial correlations in microarray data.

Microarray experiments are providing a huge amount of genome-wide data on gene expression. Many prior expression analyses have focused on inferring functional relationships (1––7); however, the quality control and normalization of the raw data that result from microarrays have received less attention. Here we address a systematic error that arises from microar-rays and discuss current methods t...

Functional genomics by data mining in DNA microarray data

The DNA microarray is a new tool for rapid and efficient collection of gene expression data. Several thousand genes can be tested simultaneously, and up or down regulation of genes as a function of time and changes in experimental conditions can easily be identified. Such changes may be external stress, disease (e.g. cancer), drugs or simply natural development. From this information networks o...

A Review of DNA Microarray Data Analysis